Gelis River is the largest river that divides in the middle of the Holy City. The current condition of the Gelis river is very alarming because the water is black and has an unpleasant odor. The variety of human activities around the Gelis River greatly affects the river and human ecosystems themselves. Therefore, a solution is needed in overcoming this problem in order to create clean and pollutant-free waters. This study aims to improve the quality of river water in Sungai Gelis using a combination of apu-ape bioremediation and nano-zeolite material. This study uses a completely randomized design consisting of 4 treatments with 3 replications. The treatment in this study included P0: Control (without apu - apu and nano zeolite), P1: Gelis river water was reheated with apu - apu plant, P2: Gelis river water was treated with nano zeolite, and P3: Gelis river water was treated with plants apu - apu and nano zeolite. Testing of Sungai Gelis wastewater is carried out in physics, chemistry and biology. The results showed that the combination of apu-apu and nanozeolite obtained clear water quality, odorless, pH became normal, and no microorganisms