Islamic business ethics is a business activity carried out by a businessman and runs his business in accordance with Islamic law with the existence of Islamic business ethics, it is expected that business people will carry out in accordance with the demands of Islamic law that have been regulated in the Al-Qur’an. Discipline is an attitude of mutual respect and appreciation, obeying applicable regulations in accordance with agreements that have been mutually agreed from the start . compensation is an acceptance as reward from giving work to the recipient of work for a job or service that has been done. The purpose of  this study was to determine Islamic business ethics, work discipline, and compensation have a significant effect on employee job satisfaction in sharia’ah  cooperatives 212. This study uses quantitative methods. The data analysis is linear regression. The data processing method in this study used the SPSS 16 program. The sampling technique used in this study was a saturated sample technique, that is all of the population was sampled. Amounting to 35 respondents. The data retrieval used was a questionnaire or questionnaire distributed to employees of  the 212 shari’ah cooperative through the google from. The results of this study indicate that Islamic business ethics has no significant effect on employee job satisfaction in sharia’ah cooperatives 212, work discipline has a significant effect on employee job statisfactionin sharia’ah cooperatives 212, and compensation has a significant effects on employee job satisfaction in cooperatives shari’ah 212 with this conclusion, Islamic business ethics, work discipline, and compensation simultaneously have a significant effect on employee job satisfaction in shari’ah 212 cooperatives.