The production of shallots in Indonesia continues to increase from year to year, and is balanced with the level of public consumption of shallots which is quite large. Therefore, increasing the production and quality of shallots can be done through improved cultivation with the pot cultivation model by taking into account the composition of the right planting media. This study aimed to determine the interaction between microbial concentration and vermicompost dose on the growth and yield of shallot (Allium ascolonicum L.). This study was a pot experiment using a factorial randomized block design (RAK) consisting of 12 treatments, 3 combinations of microbial concentration (0.25.50 ml L-1). With a dose of vermicompost (0, 100, 200, 300 g pot-1). The results of this study stated that there was no significant interaction with plant growth, except for plant height. In general, the given microbial concentration gave the same good growth and yield. While the dose of vermicompost 0-50 ml L-1 also gave the same effect, but there was a tendency that the more doses given gave better results. These results also mean that the application of microbes with increasing concentrations has not been able to reduce the dose of vermicompost applied.