Abstract Systematic review aims to analyze the impact of interventions that mediated by peers on children with special needs in an inclusion setting. The review was conducted with the search keywords "peers" and "inclusive class", "peers" and "inclusion settings", "peers" and "inclusive settings", "peers" and "inclusive classrooms" in 2 online databases, namely ERIC and ScienceDirect. There were 11 articles reviewed from the total number of initial searches of 1,233 obtained from screening results according to inclusion and exclusion criteria. The results show that all interventions that have been implemented involve the role of peers. The focus of interventions various kinds, ranging from children aged 3-16 years and more focus on children with Autism Spectrum Disorder (ASD). Eleven Interventions that involve peers are significantly able to improve interaction, communication, social skills and social initiation in children with special needs so that it can be a reference in the process of intervention in the further application or research.   Abstrak Sistematik review bertujuan untuk menganalisis dampak intervensi yang dimediasi oleh teman sebaya pada anak berkebutuhan khusus di setting inklusi. Review dilakukan dengan kata kunci pencarian “peers” and “inclusive class”, “peers” and “inclusion setting”, “peers” and “inclusive setting”, dan “peers” and “inclusive classroom” pada 2 database online, yakni ERIC dan ScienceDirect. Terdapat 11 artikel yang direview dari jumlah total pencarian awal 1.233 yang diperoleh dari hasil screening sesuai dengan kriteria inklusi dan eksklusi. Hasil menunjukkan bahwa seluruh intervensi yang telah diterapkan melibatkan peran teman sebaya. Fokus intervensi beraneka ragam, mulai dari anak berusia 3-16 tahun dan lebih banyak fokus pada anak dengan Autism Spectrum Disorder (ASD). Sebelas Intervensi yang melibatkan teman sebaya tersebut secara signifikan mampu meningkatkan interaksi, komunikasi, keterampilan sosial dan inisiasi sosial pada anak berkebutuhan khusus sehingga dapat menjadi rujukan dalam proses intervensi pada penerapan selanjutnya.     Kata Kunci: Intervensi; Teman Sebaya; Kebutuhan Khusus; Inklusi