<p align="center"> </p><p><strong><em>Background:</em></strong><em> Hospital put patient safety as priority such as decubitus prevention to provides excellent service. The incidence of decubitus commonly occurs, such as in Western Europe generally occurs about 49%, 22% in North America, 50% in Australia, 29% in Jordan, and 33% in Indonesia. Nursing interventions to prevent decubitus is an indicator to assure the quality of nursing care. Nurses influenced by various factors toward decubitus prevention. </em></p><p><strong><em>Objectives: </em></strong><em>Aim’s of this study is to analyze the factors that influence nurses through decubitus prevention on bed rest patient. </em></p><p><strong><em>Methods: </em></strong><em>The population was all nurses in Intensive Care Unit at Ulin Hospital Banjarmasin (n=30)  this study used a cross sectional approach. Instrument research is a questionare and abservastion sheet which adopted from NPUAP 2014. The statistical test used multiple logistic regression with significance level of 0,05. </em></p><p><strong><em>Results: </em></strong><em>A multivariate results found that factors associated with decubitus prevention are knowledge (0,401), attitude (0,464), encouragement nurses (0,530), and facilities and infrastructure (0,530), p-value &lt; 0,05. </em></p><p><em> </em><strong><em>Conclusions: </em></strong><em>The most related factors that influence toward decubitus prevention are knowledge, attitude, facilities and infrastructure, and encouragement nurses.</em></p><p> </p><strong>Keywords</strong>: <em>decubitus prevention, facilities and infrastructure support, fellow nurse supports, knowledge, nurse’s attitude</em>