<p><strong>Background:</strong> Coronary artery disease caused disturb of physical, psychological, and social aspects on quality of life. The aims in this study was to examine effecting factors of quality of life (QoL).</p><p><strong>Methods:</strong> In this used the analytic correlation with cross-sectional design. One hundred and three subjects paticipated with purposive sampling (88 male and 23 female). QoL quesioner (SF-36) were used to collect the data. The data were analyzed by multivariate regression.</p><p><strong>Results: </strong>One<strong> </strong>hundred and three patientss (80 males and 23 female) were enroll on this study. In this study indicates that independent variables were not associated with quality of life (p value &gt; 0.05). The greater quality of life found in patients graduated from university (62,2%) and had much income (51.9%). Other variables like male (57.5%), patients between 48-57 years of ages (68.2%), married patients with coronary artery disease (62.0%), the retired or unemplayee (78.9%), patients with hypertention (57.8%), never taking alcohol (60.8%), never smoking (50%) and never doing exercise (66%) had lower quality of life score.</p><strong>Conclusion: </strong>There were no statistically significant factors affecting quality of life in patients with CAD. The more respondents needed to know the factors affecting quality of life<strong><em><br /></em></strong><em></em>