This study aims to design and create interactive multimedia learning modules that meet Valid, Practical and Effective requirements for operating system subjects in Vocational High School. The type of this research is Research and Development research conducted in Vocational High School class 10. The population of this study is the students of class 10 SMK Negeri Batipuh West Sumatra. The sample of this research is students of class 10 Multimedia SMK N Batipuh West Sumatra. The results of the assessment of the three validators overall validator assessment of the Interactive multimedia learning module amounted to 83.93 percent so that the validity level can be interpreted Valid is used. Overall assessment of the practicality level of use Interactive multimedia learning module as a learning resource of 89.19 percent, so the level of practicality can be interpreted Very Practical use and the effectiveness assessment of Interactive multimedia learning module as a learning resource of 86.90 percent so that the level of effectiveness can be interpreted Very Effective use.  Keywords: Adobe Director, Interactive Multimedia Module, Operating System