This study aims at analyzing the reflection of IRF (Initiation-Response-Feedback) in speaking class and investigating the dominant sequence among I, R and F. IRF is a pattern of classroom interaction found by Sinclair and Coulthard in 1975 that stands for teacher initiation, students’ response and feedback by teacher. Initiation is the movement in which teacher initiates an interaction to get the response of the students, then teacher gives feedback to the students’ response. To obtain the data, the researcher conducted classroom observation in speaking class in one university in West Java. The result showed that student response becomes the dominant sequence of IRF in speaking class. Furthermore, it is recommended that the teachers should maintain the effectiveness of classroom interaction and give much opportunity to the students to take role in classroom verbal interaction through reflecting the IRF pattern in teaching learning process particularly in speaking classroom.Keywords: IRF, classroom interaction, speaking class