In social context, the common reality indicates that women becoming victim of men’s suppression. In modern terminology, the suppression is called “misogyny” meaning direct or indirect suppression on women whether in a rude or soft manner. The suppression itself occurs since men (including Moslems) do not have gender awareness and sensitivity. The awareness on women inequality has been detected since the presence of gender analysis in sociology. This paper focuses on the perception of women marginality in terms of the anatomy, theological vision, and historical experience. The perception of marginality does not immediately judge on the superiority of men towards women and the marginality of women. This perception appears since the different divison of role between men and women has become an important part of human civilization dynamics. The perception on women marginality is then irrelevant correlated to the guidance applied by the Prophet Muhammad saw that gave the same chance among men and women. For this reason, the concept of equality between men and women has a significant root and foundation in religious texts.