This research aimed to describe the interaction between Islam and Tolakitradition in South East Sulawesi. The interaction between Tolaki and Islamhas two formulations, the first, Islam contaminated, changed and reformed localculture, Tolaki. This kind of formulation produced the reality of religious sociallife like barasandi (bersanji/aqiqah), a marriage procession (mowindahako), acelebration of circumcision (maggilo), a celebration such a praying for being savedfrom any problem of life, a celebration of  Prophet of  Muhammad birth (mauluNabi), religious activities, an art and literature like kinoho agama (religiouspoems), Taenango langgai saranani (the history of heroic in Islamic spreading orproselytization in Tolaki region), religious social life like how someone performed orpilgrimaged to Mecca  (hadi kobaraka), and the dynamics of social organizationlife. The second, Islam was contaminated by several local traditions. This caseproduced the process of Islam localizing in the the dynamics of Tolaki religioussocial community. There had been an interaction form and acculturation betweenIslam and Tolaki culture in Southeast Sulawesi.