This study aims to determine the effect of mind mapping learning strategy on student learning outcomes on excretory system material in XI Science class. The research method used in this research is quasi experimental method with design non - randomized Control Group Pretest-Postest Design . The population in this study includes all XI science class in senior high school which amounts to 60 students. The sampling technique used sampling saturated with class XI Science 1 which amounted to 30 students as experimental class and class XI Science 2 which amounted to 30 students as control class. The instrument used in this research is written test in the form of pretest and posttest to measure student learning result cognitively. The first stage data analysis of the average value of pretest in experimental class is 47.50 while the control class is 49.50. After applying the mind mapping strategy , the average grade of post experiment class increased with the average value of 83.33 which is very good while the mean score of posttest of control class is 73,2 which is good. The calculation results are known that there is influence a significant application of mind mapping learning strategy to student learning outcomes. Keywords: learning, mind mapping, result study, excretory system