The Effect of Tomate Juice On Trigliserida Levels Of Male White Rats Induced by Alloxan

Authors

  • FITRI HANDAJANI HANG TUAH UNIVERSITY
  • Ibrahim Shihatta Universitas Hang Tuah

DOI:

https://doi.org/10.33086/mhsj.v5i1.1740

Keywords:

Tomato juice (Solanum lycopersicum), Serum triglyceride levels, alloxan

Abstract

Background: Tomato juice is believed to affect triglyceride levels in the blood because it contains lycopene. This study aims to determine the effect of tomato juice (Solanum lycopersicum) on blood triglyceride levels in the wistar strain of male Rattus norvegicus induced by alloxan.

Methods: 24 were divided into 3 groups, (1) Group K (-) experimental animals without treatment, (2) Group K (+) experimental animals induced by alloxan 150 mg / kgBB, (3) Treatment group K (P) animals tried alloxan induced 150 mg / kg and got 1.75 ml / head of tomato juice.

Results: There was a significant difference in mean triglyceride levels between groups K (-) and group K (+). This indicates that the induction of alloxan increases blood triglyceride levels. There were significant differences in the mean triglyceride levels between the K (+) and K (P) groups because tomato juice contained lycopene which could reduce triglyceride synthesis.

Conclusions: Tomato juice (solanum lycopersicum) reduced wistar strain male Rattus novergicus triglyceride levels induced by alloxan.

 

Downloads

Download data is not yet available.

References

Anindhita Yuriska. (2009). Efek Aloksan Terhadap Kadar Glukosa Darah Tikus Wistar. Fakultas Kedokteran Universitas Diponegoro Semarang, 1-45.

Arifnaldi MS, 2014. Hubungan kadar Trigliserida dengan kejadian stroke iskemik di RSUD Sukoharjo, Fakultas kedokteran Surakarta

Astuti, Y. D. W. I. (2012). Pengaruh pemberian jus tomat terhadap kadar glukosa darah pada prediabetes.

Ekawati, E. R. (2012). Hubungan Kadar Glukosa darah Terhadap Hypertriglyceridemia Pada Penderita Diabetes Mellitus. Seminar Nasional Kimia UNESA, 2-3. https://doi.org/ISBN : 978-979-028-550-7

Hernani dan Rahardjo. (2005). Tanaman Berkhasiat Antioksidan, 3-5.

Ii, B. A. B., & Pustaka, T. (2012). Gambar 1. Rumus molekul trigliserida Sumber : Biokimia Harper, 2009 repository.unimus.ac.id, 1–13.

Kemenkes RI. (2014). Situasi dan Analisis Diabetes. Pusat Data Dan Informasi Kementerian Kesehatan RI. https://doi.org/24427659

Lenzen S., 2008. The mechanisms of alloxan- and treptozotocin-induced diabetes Diabetologia. Vol 51:216–226

Palazo p, Catalano A, Simone RE, Mele MC, citaddini A, 2012. Effect of lycopene and tomato product on cholesterol metabolism; Annals of Nutrition & Metabolism, vol. 61. iss 2

Rao, Venket, 2004. Processed tomato products as a source of dietary lycopene: bioavailability and antioxidant properties. Canadian journal of dietetic practice and research. Vol. 65. Iss 4,pp. 161-165

Sunarmani, Kun Tanti, D., 2008, Parameter Likopen Dalam Standardisasi Konsentrat Buah Tomat, Prosiding PPI Standardisasi, Jakarta.

Kim Y, Hirai S, Goto T, Ohyane C, Takahashi, Tsugane, Konishi, Fujii, Inai, 2012. Potent PPARα Activator Derived from Tomato Juice, 13-oxo-9,11-Octadecadienoic Acid, Decreases Plasma and Hepatic Triglyceride in Obese Diabetic Mice. PLos One. 7(2)

Downloads

Published

2021-09-23

How to Cite

HANDAJANI, F., & Shihatta, I. . (2021). The Effect of Tomate Juice On Trigliserida Levels Of Male White Rats Induced by Alloxan. Medical and Health Science Journal, 5(1), 20–25. https://doi.org/10.33086/mhsj.v5i1.1740

Issue

Section

Articles